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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3E
All Species:
18.48
Human Site:
S449
Identified Species:
36.97
UniProt:
Q9NVU0
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NVU0
NP_060589.1
708
79898
S449
P
K
K
P
D
A
Q
S
G
P
A
G
L
V
C
Chimpanzee
Pan troglodytes
XP_511201
793
88472
S537
P
K
K
P
D
A
Q
S
G
P
A
G
L
V
S
Rhesus Macaque
Macaca mulatta
XP_001086444
913
101038
S653
P
K
K
P
D
A
Q
S
G
P
A
G
L
V
S
Dog
Lupus familis
XP_850881
880
98461
L648
W
T
G
I
Q
A
K
L
E
K
V
Y
N
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZT4
710
79836
S449
P
K
K
P
D
G
Q
S
A
P
V
G
L
V
S
Rat
Rattus norvegicus
NP_001101973
708
79794
S449
P
K
K
P
D
G
P
S
A
P
V
V
S
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507137
701
79464
S449
P
K
K
P
D
G
Q
S
V
P
S
V
L
V
S
Chicken
Gallus gallus
XP_414921
318
36190
H89
V
Y
R
K
G
E
L
H
L
T
P
L
H
G
I
Frog
Xenopus laevis
NP_001085230
701
79451
S449
M
S
K
K
P
D
T
S
S
A
P
P
V
V
I
Zebra Danio
Brachydanio rerio
NP_997919
696
78706
I450
V
H
K
K
D
V
Q
I
E
P
V
H
F
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524192
486
54961
H257
K
L
L
P
Y
D
E
H
V
Q
T
V
A
P
A
Honey Bee
Apis mellifera
XP_397129
499
57790
L270
V
S
N
Y
V
T
S
L
N
Y
I
R
T
L
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
74.5
64.3
N.A.
92.2
92.2
N.A.
87.4
38.4
70.1
65.6
N.A.
25.1
32.9
N.A.
N.A.
Protein Similarity:
100
87.3
76.1
67.3
N.A.
95
95.3
N.A.
91.8
41.8
82.7
79.9
N.A.
43.3
48
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
6.6
N.A.
73.3
46.6
N.A.
66.6
0
20
26.6
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
20
N.A.
73.3
46.6
N.A.
73.3
6.6
26.6
26.6
N.A.
13.3
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
34
0
0
17
9
25
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
59
17
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
9
9
0
17
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
9
0
9
25
0
0
25
0
0
34
0
17
9
% G
% His:
0
9
0
0
0
0
0
17
0
0
0
9
9
0
0
% H
% Ile:
0
0
0
9
0
0
0
9
0
0
9
0
0
0
17
% I
% Lys:
9
50
67
25
0
0
9
0
0
9
0
0
0
0
0
% K
% Leu:
0
9
9
0
0
0
9
17
9
0
0
9
42
17
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
9
0
0
0
9
0
0
% N
% Pro:
50
0
0
59
9
0
9
0
0
59
17
9
0
9
9
% P
% Gln:
0
0
0
0
9
0
50
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
0
17
0
0
0
0
9
59
9
0
9
0
9
9
34
% S
% Thr:
0
9
0
0
0
9
9
0
0
9
9
0
9
0
0
% T
% Val:
25
0
0
0
9
9
0
0
17
0
34
25
9
50
9
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
9
9
0
0
0
0
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _